Topical glyoxylic acid may be to blame for the women's injuries, doctors say
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Medical professionals are warning about the potential side effects of certain hair treatments after a young woman sustained kidney injuries after a session at a salon.
A 26-year-old Tunisian woman suffered from three acute kidney injuries between June 2020 and July 2022, according to a piece that was published in the New England Journal of Medicine this month. The letter to the editor, which was written by French doctors, linked certain smoothing and straightening hair products to kidney damage.
The woman in the case study had no previous health issues when she sought medical help. She suffered from vomiting, fever, diarrhea and back pain when she approached the doctor.
"Each episode of acute kidney injury had coincided with a hair treatment at the same salon on the day the symptoms began," the journal letter explained.
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A 26-year-old Tunisian woman suffered from acute kidney injuries after a hair-straightening proceedure. (iStock)
"The patient reported a burning sensation during each procedure, followed by scalp ulcers."
Upon examination, medical staff found that her blood tested positive for increased plasma creatinine levels. Plasma creatinine is a waste product that comes from muscles – when it enters the blood, it is filtered out by kidneys.
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When the woman went to the salon, the hairstylist would apply a cream on her hair that contained 10% glyoxylic acid. That chemical is what researchers believe caused the kidney damage.
"These results provide evidence that hair-straightening cream containing glyoxylic acid is responsible for calcium oxalate–induced nephropathy after hair-straightening procedures of the type described here," the letter argues. "Glyoxylic acid was patented and introduced recently in hair-straightening products as a seemingly safer alternative to formulations containing formaldehyde."
Medical researchers suggest that the 10% glyoxylic acid in the hair product caused the kidney damage. (iStock)
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"In consideration of the potential nephrotoxicity of topical glyoxylic acid, products containing this compound should be avoided and, we would proffer, discontinued from the market."
The article also noted that 26 patients in Israel suffered acute kidney injuries after "Brazilian-style" hair-straightening procedures.
The New England Journal of Medicine piece suggests that women avoid topical glyoxylic acid. (iStock)
In 2022, a National Institutes of Health (NIH) study suggested that chemical hair-straightening products may increase women's risk of uterine cancer. Researchers pointed to endocrine-disrupting chemicals in the products.
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Andrea Vacchiano is a breaking news writer for Fox News Digital and Fox Business. You can follow her on X at @andrea_vacch or send story tips to
